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pentobarbital will reduce the level or impact of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will minimize the level or impact of alprazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.pentobarbital will decrease the extent or outcome of amlodipine by